cytoreductive surgery: is a procedure to remove the cancerous tissues from the abdomen. This is a major surgery which removes all visible evidence of disease from the abdomen. It involves removal of disease from peritoneum, omentum and abdominal viscera. This systemic procedure may also involve resection and reanastomosis of part of bowel for complete removal of disease. This adequacy of long cytoreductive surgery is the decisive factor to further proceed with HIPEC. When as many tumors as possible have been removed, a heated, sterilized chemotherapy solution is delivered to the abdomen to penetrate and destroy remaining cancer cells. The solution is 41 to 42 degrees Celsius, about the temperature of a warm bath. It’s circulated throughout the abdomen for approximately 90 minutes. The solution is then drained from the abdomen, and the incision is closed.
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a surgical procedure that’s giving new hope to patients with abdominal cancers. Immediately after removing visible tumors a heated, sterilized highly concentrated dose of chemotherapy solution is circulated inside the abdominal cavity at a temperature of around 42 degree Celsius. The drug penetrate and destroy microscopic cancer cells directly.
Cytoreductive Surgery is a very long and challenging surgery. Depending on site of tumors to be removed, operation can take as many as eight or nine hours, and chemotherapy application takes another two hours. There are requirements of blood products and post surgery ICU care. Patient may need nutritional support.
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